Ruprecht-Karls-Universität Heidelberg






Search pubmed for publications by Victor Sourjik.





Di Ventura, B., Knecht, B., Andreas, H., Godinez, W.J., Fritsche, M., Rohr, K., Nickel, W., Heermann, D.W. and Sourjik, V. Chromosome segregation by the Escherichia coli Min system. Mol. Syst. Biol. (2012) 9: 686.

Neumann, S., Grosse, K. and Sourjik, V. (2012). Chemotactic signaling via carbohydrate phosphotransferase systems in Escherichia coli. Proc. Natl. Acad. Sci. USA 109: 12159-12164.

Kumar, M and Sourjik, V. Physical map and dynamics of the chaperone network in Escherichia coli. Mol. Microbiol (2012) 84: 736-47. Mar 30, (ePub).

Lan, G., Sartori, P., Neumann, S., Sourjik, V. and Tu, Y. (2012). The energy-speed-accuracy trade-off in sensory adaptation. Nature Phy. 8: 422-428.

Zarbiv, G., Li, H., Wolf, A., Cecchini, G., Caplan, S.R., Sourjik, V. and Eisenbach, M. Energy complexes are apparently associated with the switch-motor complex of bacterial flagella. J. Mol. Biol. (2012) 416:192-207. Epub 2011, Dec 19.

Sourjik, V. and Wingreen, N.S. Responding to chemical gradients: bacterial chemotaxis. Curr Opin Cell Biol (2012), 24:262-8, (ePub) Dec 8 2011.

Steuer, R. , Waldherr, S., Sourjik, V. and Kollmann, M. Robust signal processing in living cells. PLoS Comput Biol (2011) 7:e1002218.

Schulmeister, S., Grosse, K. and Sourjik, V. Effects of receptor modification and temperature on dynamics of sensory complexes in Escherichia coli chemotaxis. BMC Microbiol (2011) 11:222.

Oleksiuk, O., Jakovljevic, V., Vladimirov, N., Carvalho, R., Paster, E., Ryu, WS., Meir, Y., Wingreen, NS., Kollmann, M. and Sourjik, V. Thermal robustness of signaling in bacterial chemotaxis. Cell (2011) 145:312-321.

Khursigara, C.M., Lan, G., Neumann, S., Wu, X., Ravindran, S. Borgnia, M.J., Sourjik, V., Milne, J., Tu, Y. and Subramaniam, S. Lateral density of receptor arrays in the membrane plane influences sensitivity of the E. coli chemotaxis response. EMBO J. (2011), 30(9):1719-29, Mar 25 (Epub).

Lan, G., Schulmeister, S., Sourjik, V., and Tu, Y. Adapt locally and act globally: strategy to maintain high chemoreceptor sensitivity in complex environments. Mol. Syst. Biol. (2011) 7:475.

Kuhn, P., Weiche, B. Sturm, L., Sommer, E., Drepper, F., Warscheid, B., Sourjik, V. and Koch, H.G. The bacterial SRP receptor, SecA and the ribosome use overlapping binding sites on the SecY translocon. Traffic (2011), 12:563-78, Epub Jan. 21, 2011.

Di Ventura, B. and Sourjik, V. Self-organized partitioning of dynamically localized proteins in bacterial cell division. Mol. Syst. Biol. (2011). 7:457.

Li, H. and Sourjik, V. Assembly and stability of flagellar motor in Escherichia coli. Mol Microbiol. (2011), 80:886-99, (Epub 2011 Jan 19).

Meir Y, Jakovljevic, V, Oleksiuk O, Sourjik V, Wingreen, NS. Precision and kinetics of adaptation in bacterial chemotaxis. Biophys J. (2010), 99(9):2766-74.

Neumann S, Hansen CH, Wingreen NS, Sourjik V. Differences in signalling by directly and indirectly binding ligands in bacterial chemotaxis. EMBO J. (2010), 29(20):3484-95. (Epub 2010 Sep 10).

Hansen CH, Sourjik V, Wingreen NS. A dynamic-signaling-team model for chemotaxis receptors in Escherichia coli. Proc Natl Acad Sci U S A. (2010) 107(40):17170-5. (Epub 2010 Sep 20).

Stöhr K, Siegberg D, Ehrhard T, Lymperopoulos K, Oz S, Schulmeister S, Pfeifer AC, Bachmann J, Klingmüller U, Sourjik V, Herten DP. Quenched Substrates for Live-Cell Labeling of SNAP-Tagged Fusion Proteins with Improved Fluorescent Background. Anal Chem. 2010 Oct 1;82(19):8186-93.

Sourjik, V. and Armitage, J.P. Spatial organization in bacterial chemotaxis. EMBO J. (2010) 29:2724-2733.

Kentner, D., Sourjik, V. Use of fluorescence microscopy to study intracellular signaling in bacteria. Annu. Rev. Microbiol. 2010 Oct 13; 64:373-390. Epub 2010 Jun 7.

Clausznitzer D, Oleksiuk O, Løvdok L, Sourjik V, Endres RG. Chemotactic response and adaptation dynamics in Escherichia coli. PLoS Comput Biol. 2010 May 20;6(5):e1000784.

Vladimirov N, Lebiedz D, Sourjik V. Predicted auxiliary navigation mechanism of peritrichously flagellated chemotactic bacteria. PLoS Comput Biol. 2010 Mar 19;6(3):e1000717.

Boehm A, Kaiser M, Li H, Spangler C, Kasper CA, Ackermann M, Kaever V, Sourjik V, Roth V, Jenal U. Second messenger-mediated adjustment of bacterial swimming velocity. Cell. 2010 Apr 2;141(1):107-16. Epub 2010 Mar 18.

Kumar, M., Mommer, M.S., Sourjik,V. Mobility of cytoplasmic, membrane, and DNA-binding proteins in Escherichia coli.
Biophys J. 2010 98:552-559.

Kalinin, Y., Neumann, S., Sourjik, V., Wu, M. J. Responses of Escherichia coli bacteria to two opposing chemoattractant gradients depend on the chemoreceptor ratio. Bacteriol. (2010) 192:1796-1800. (Epub).

Winkler, J., Seybert, A., Koenig, L., Pruggnaller, S., Haselmann, U., Sourjik, V., Weiss, M., Frangakis, A.S., Mogk, A., Bukau, B. Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageing. EMBO J. (2010) 29:910-923. (Epub).

Vladimirov, N., Sourjik, V. Chemotaxis: how bacteria use memory. Biol Chem. (2009) 390, 1097-1104.

Løvdok, L., Bentele, K., Vladimirov, N., Müller, A., Pop, F.S., Lebiedz, D., Kollmann, M., Sourjik, V. Role of translational coupling in robustness of bacterial chemotaxis pathway. PLoS Biol. (2009) 7:e1000171.

Kentner, D., Sourjik, V. Dynamic map of protein interactions in the Escherichia coli chemotaxis pathway. Mol. Syst. Biol. (2009) 5:238.

Vladimirov, N., Løvdok, L., Lebiedz, D., Sourjik, V. Dependence of bacterial chemotaxis on gradient shape and adaptation rate. PLoS Comput Biol. (2008) 4:e1000242.

Endres, R.G., Oleksiuk, O., Hansen, C.H., Meir, Y., Sourjik, V., Wingreen, N.S. Variable sizes of Escherichia coli chemoreceptor signaling teams. Mol Syst Biol. (2008) 4:211.

Plaimas, K., Mallm, J.P., Oswald, M., Svara, F., Sourjik, V., Eils, R., Koenig, R. Machine learning based analyses on metabolic networks supports high-throughput knockout screens. BMC Syst Biol. (2008) 2:67.

Thiem, S., Sourjik, V. Stochastic assembly of chemoreceptor clusters in Escherichia coli. Mol Microbiol. (2008) 68:1228-1236.

Schulmeister, S., Ruttorf, M., Thiem, S., Kentner, D., Lebiedz, D., Sourjik, V. Protein exchange dynamics at chemoreceptor clusters in Escherichia coli. Proc Natl Acad Sci U S A. (2008) 105:6403-6408. Epub 2008.


Sourjik, V. and Wingreen, N.S. (2007) Turning to the cold. Nat. Cell Biol. 9:1029-1031.

Sourjik, V., Vaknin, A., Shimizu, T.S., Berg, H.C. (2007) In Vivo Measurement by FRET of Pathway Activity in Bacterial Chemotaxis. Methods Enzymol. 423:363-391.

Lovdok, L., Kollmann, M., Sourjik, V. (2007) Co-expression of signaling proteins improves robustness of the bacterial chemotaxis pathway. J. Biotechnol. 129:173-180.

Thiem, S., Kentner, D., Sourjik, V. (2007) Positioning of chemosensory clusters in E. coli and its relation to cell division. EMBO J. 26:1615-1623.

Kollmann, M., Sourjik, V. (2007) In silico biology: from simulation to understanding. Curr. Biol. 17:R132-134.

Kentner, D., Sourjik, V. (2006) Spatial organization of the bacterial chemotaxis system. Curr. Opin. Microbiol. 9:619-624.

Kentner, D., Thiem, S., Hildenbeutel, M., Sourjik, V. (2006) Determinants of chemoreceptor cluster formation in Escherichia coli. Mol. Microbiol., 61: 407-417.

Kollmann, M., Lovdok, L., Bartholome, K., Timmer, J., Sourjik, V. (2005) Design principles of a bacterial signalling network. Nature, 438:504-507.

Michalodimitrakis, K.M., Sourjik, V., Serrano, L. (2005) Plasticity in amino acid sensing of the chimeric receptor Taz. Mol. Microbiol., 58: 257-266.

Sourjik, V. (2004) Receptor clustering and signal processing in E. coli chemotaxis. Trends Microbiol., 12: 569-576 (see manuscript).

Liberman, L., Berg, H. C., and Sourjik, V. (2004) Effect of chemoreceptor modification on receptor-kinase complex assembly and activity in Escherichia coli. J. Bacteriol., 186, 6643-6646.

Sourjik, V. and Berg, H. C. (2004) Functional interactions between receptors in bacterial chemotaxis. Nature, 428: 437-441.

Sourjik, V. and Berg, H. C. (2002b) Binding of the Escherichia coli response regulator CheY to its target measured in vivo by fluorescence resonance energy transfer. Proc. Natl. Acad. Sci. USA, 99: 12669-12674.

Sourjik, V. and Berg, H. C. (2002a) Receptor sensitivity in bacterial chemotaxis. Proc. Natl. Acad. Sci. USA 99: 123-127.

Sourjik, V. and Berg, H.C. (2000) Localization of components of the chemotaxis machinery of Escherichia coli using fluorescent protein fusions. Mol. Microbiol. 37:740-751.

Sourjik, V., Muschler, P., Scharf, B., and Schmitt, R. (2000) VisN and VisR are global regulators of chemotaxis, flagellar, and motility genes in Sinorhizobium (Rhizobium) meliloti. J. Bacteriol. 182:782-788.

Sourjik. V., Sterr, W., Platzer, J., Bos, I., Haslbeck, M., and Schmitt, R. (1998) Mapping of 41 chemotaxis, flagellar and motility genes to a single region of the Sinorhizobium meliloti chromosome. Gene. 223:283-290.

Sourjik, V., and Schmitt, R. (1998) Phosphotransfer between CheA, CheY1, and CheY2 in the chemotaxis signal transduction chain of Rhizobium meliloti. Biochemistry. 37:2327-2335.

Sourjik, V., and Schmitt, R. (1996) Different roles of CheY1 and CheY2 in the chemotaxis of Rhizobium meliloti. Mol. Microbiol. 22:427-436.

Greck, M., Platzer, J., Sourjik, V., and Schmitt, R. (1995) Analysis of a chemotaxis operon in Rhizobium meliloti. Mol Microbiol. 15:989-1000.