Ruprecht-Karls-Universität Heidelberg

Publications by the Gruss Lab


Search pubmed for publications by Oliver Gruss



- Kulturmus, B., Wang, W., Ruppert, T., Neuner, A., Cerikan, B., Viol, L., Duenas-Sanchez, R., Gruss, O.J. and Pereira, G. WDR8 is a centriolar satellite and centriole-associate protein that promotes ciliary vesicle docking during ciliogenesis, J Cell Sci, accepted for publication (2015)

- Chinen, T., Liu, P., Shioda, S., Pagel, J., Cerikan, B., Lin, T. C., Gruss, O.J., Hayashi, Y., Takeno, H., Shima, T., Okada, Y., Hayakawa, I., Kigoshi, H., Usui, T., Schiebel, E, 2015 The gamma-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. Nat Commun. 6, 8722-30

- Husedzinovic A, Neumann B, Reymann J, Draeger-Meurer S, Chari A, Erfle H, Fischer U, Gruss OJ. The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization. Mol Biol Cell. 2014 Nov 12. pii: mbc.E14-06-1151.

- Tegha-Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, Gruss OJ.
MAP1S controls microtubule stability throughout the cell cycle in human cells J Cell Sci.2014 Oct 9.pii: jcs. 136457.

- Neumayer G, Belzil C, Gruss OJ, Nguyen MD. TPX2: of spindle assembly, DNA damage response and cancer. Cell Mol Life Sci. Feb21 (2014)

- Husedzinovic A, Oppermann F, Draeger-Meurer S, Chari A, Fischer U, Daub H, Gruss OJ. Phosphoregulation of the human SMN complex. Eur J Cell Biol. Feb11 (2014)

- Yokoyama H, Koch B, Walczak R, Ciray-Duygu F, González-Sánchez JC, Devos DP, Mattaj IW, Gruss OJ. The nucleoporin MEL-28 promotes RanGTP-dependent g-tubulin recruitment and microtubule nucleation in mitotic spindle formation. Nat Commun. 5:3270, Feb10 (2014)

- Klinger M, Wang W, Kuhns S, Baerenz F, Draeger-Meurer S, Pereira G, Gruss OJ. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 25(4):495-507, Feb (2014)


- Yokoyama H, Gruss OJ. New Mitotic Regulators Released from Chromatin. Fron Oncol. 3:308.eCollection 2013. Review. Dec 16 (2013)

- Tuerbachova I, Schwachula T, Vasconcelos I, Mustea A, Baldinger T, Jones KA, Bujard H, Olek A, Olek K, Gellhaus K, Braicu I, Koensgen D, Fryer C, Ravot E, Hellwag A, Westerfeld N, Gruss OJ, Meissner M, Hasan MT, Weber M, Hoffmueller U, Zimmermann S, Loddenkemper C, Mahner S, Babel N, Berns E, Adams R, Zeilinger R, Baron U, Vergote I, Maughan T, Marme F, Dickhaus T, Sehouli J, Olek S. The cellular ratio of immune tolerance (immunoCRIT) is a definite marker for aggressiveness of solid tumors and may explain tumor dissemunation patterns. Epigenetics. 8(11): 1226-35, Nov (2013)

- Hofmann JC, Tegha-Dunghu J, Draeger-Meurer S, Will CL, Lührmann R, Gruss OJ. The Prp19 complex directly functions in mitotic spindle assembly. PLoS One. 8(9): e74851, Sep 19 (2013)

- Baerenz F, Inoue D, Yokoyama H, Tegha-Dunghu, J, Freiss S, Draeger S, Mayilo D, Cado I, Merker S, Hoeckendorf B, Pilz S, Steinbeisser H, Lorenz H, Ruppert T, Wittbrodt J and Gruss OJ. The centriolar satellite protein SSX2IP promotes centrosome maturation. J Cell Biol, July (2013)

- Neumayer G, Helfricht A, Shim SY, Le HT, Lundin C, Belzil C, Chansard M, Yu Y, Lees-Miller SP, Gruss OJ, van Attikum H, Helleday T and Nguyen MD. Targeting Protein for Xenopus kinesin like protein 2 (TPX2) regulates g–H2AX levels upon ioninizing radition. J Biol Chem. 2012 Dec 7;287(50):42206-22. (2012)

- Schmitt K, Wolter P, Fackler M, Kremling H, Probst L, Hauser S, Gruss OJ and Gaubatz S. GAS2L3, a novel target gene of the DREAM complex, is required for proper cytokinesis. J Cell Sci, 125:2303-406. (2012)

- Oppermann F, Grundner-Culemann K, Kumar C, Gruss OJ, Jallepalli PV and Daub H. Combination of chemical genetics and phosphoproteomics for kinase signaling analysis enables confident identification of cellular downstream targets. http://www.ncbi.nlm.nih.gov/pubmed/22199227, Mol Cell Proteomics 11(4): O111.012351. (2011)

- Bärenz F, Mayilo D, Gruss OJ. Centriolar Satellites: busy orbits around the centrosome, Eur J Cell Biol. Dec;90(12):983-9. (2011)

- Berger SM, Pesold B, Reber S, Schönig K, Berger AJ, Weidenfeld I, Miao J, Berger MR, Gruss OJ, Bartsch D. Quantitative analysis of conditional gene inactivation using rationally designed, tetracycline-controlled miRNAs, Nucleic Acid Res, 38:168. (2010)

- Gruss OJ. Nuclear transport receptor goes moonlighting, Nat Cell Biol, 12: 640-41. (2010)

- Hearst SM, Gilder AS, Sandeep SN, Davis MD, George EM, Whittom AA, Toyota CG, Husedzinovic A, Gruss OJ, Herbert M.Cajal body formation correlates with differential coilin phosphorylation in primary and transformed cell lines, J Cell Sci, 122: 1872-81. (2009)

- Reber S, Over S, Kronja I and Gruss OJ. CaM kinase II Initiates meiotic spindle depolymerisation independently of APC/C activation, J Cell Biol. 183:1007-17. (2008)

- Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J and Gruss OJ. Eml3 is a nuclear microtubule binding protein required for proper alignment of chromosomes in metaphase. J Cell Sci. 121:1718-26. (2008)

- Yokoyama H, Gruss OJ, Rybina S, Caudron M, Schelder M, Wilm M, Mattaj IW and Karsenti E. Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol. 180(5):867-75. (2008)

- Petri S, Grimmler M, Over S, Fischer U, Gruss OJ. Dephosphorylation of SMN by PPM1G/PP2Cγ governs Cajal body localization and stability of the SMN complex. J Cell Biol, 179(3):451-65. (2007)

- Dumont J, Petri S, Pellegrin F, Terret ME, Bohnsack MT, Rassinier P, Georget V, Kalab P, Gruss OJ, and Verlhac MH. A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes. J. Cell Biol. 176(3):295-305. (2007)

- Godl K*, Gruss OJ*, Eickhoff J, Wissing J, Blencke S, Weber M, Degen H, Brehmer D, Orfi L, Horvath Z, Keri G, Muller S, Cotten M, Ullrich A, Daub H. Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling. Cancer Res. 65(15):6919-26.(2005) *shared first authorship

- Gruss OJ, Vernos I.The mechanism of spindle assembly: functions of Ran and its target TPX2. J Cell Biol. Sep 27;166(7):949-55. Review (2004)

- Schatz CA, Santarella R, Hoenger A, Karsenti E, Mattaj IW, Gruss OJ*, Carazo-Salas RE*. Importin alpha-regulated nucleation of microtubules by TPX2, EMBO J. 22: 2060-70. (2003) *shared last authorship

- Gruss OJ*, Wittmann M*, Yokoyama H, Pepperkok R, Kufer TA, Silljé HHW, Karsenti E, Mattaj IW, Vernos I. Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells, Nat Cell Biol., 4: 871-9. (2002) * shared first authorship

- Hetzer M, Gruss OJ, Mattaj IW. The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly, Nat. Cell Biol. 4: E177-E184. Review (2002)

- Kufer TA, Silljé HHW, Koerner R, Gruss OJ, Meraldi P, Nigg EA. Human TPX2 is required for targeting Aurora-A kinase to the spindle. J. Cell Biol. 158: 617-23. (2002)

- Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E. Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol. 3: 228-34. (2001)

- Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW. Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell 104: 83-93. (2001) *

- Hetzer M, Bilbao-Cortes D, Walther TC, Gruss OJ, Mattaj IW. GTP hydrolysis by Ran is required for nuclear envelope assembly. Mol. Cell 5:1013-24. (2000)

- Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW. Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400: 178-81. (1999)

- Gruss OJ, Feick, P, Frank R, Dobberstein B. Phosphorylation of components of the ER translocation site. Eur. J. Biochem. 260: 785-793. (1999)

 

 

 

* = equal contribution

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