Ruprecht-Karls-Universität Heidelberg

Publications by the Luke lab

Search for recent publications by the Luke lab.



Maicher A, Kastner L, Dees M and Luke B: Telomere transcription causes replication dependent telomere shortening and promotes cellular senescence. Nucleic Acids Research. 2012, epub ahead of print (see Abstract).

Ferreira H, Luke B, Schober H, Kalck V, Lingner J and Gasser S: PIAS-homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast. Nature Cell Biol. 2011 Jun 12;13(7):867-74. (see Abstract).

Iglesias N, Redon S, Pfeiffer V, Dees M, Lingner J*, Luke B*: Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast. EMBO Rep. 2011 Jun;12(6):587-93. (see Abstract).

Luke-Glaser S, Luke B, Grossi S and Constantinou A: FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling. EMBO J. 2010 Feb 17;29(4): 795-805. (see Abstract).

Chang M, Luke B, Kraft C, Li Z, Peter M, Lingner M and Rothstein R: Telomerase is essential to alleviate Pif1-induced replication stress at telomeres. Genetics. 2009 Nov;183(3):779-91. (see Abstract).

Deplazes A, Möckli N, Luke B, Auerbach D and Peter M: Yeast Uri1 promotes translation initiation and may provide a link to cotranslational quality control. EMBO J. 2009 May 20;28(10):1429-41. (see Abstract).

Luke B, Panza A,  Redon S, Iglesias N, Li Z, and Lingner J: The Rat1p 5’ to 3’ exonuclease degrades telomeric transcripts and promotes telomere elongation in S. cerevisiae.  Mol Cell. 2008 Nov 21;32(4):465-77. (see Abstract).

Zaidi IW*, Rabut G*, Poveda A , Scheel H, Hofmann K, Pasero P, Malmström J, Ulrich H, Peter M, and Luke B: Rtt101p and Mms1p form a Cul4Ddb1-like E3 ligase which promotes replication through damaged DNAEMBO Rep. 2008 Oct;9(10):1034-40. (see Abstract).

Luke B*, Azzalin C*, Hug N, Deplazes A, Peter M and Lingner J: Saccharomyces cerevisiae  Ebs1p is a putative ortholog of human SMG7 and promotes nonsense mediated mRNA decay.  Nucleic Acid Res. 2007;35(22):7688-97. (see Abstract).

Luke B, Versini G, Jaquenoud M, Zaidi IW, Kurz T, Pintard L, Pasero P, Peter M,: The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites. Curr Biol. 2006 Apr 18;16(8):786-92. (see Abstract).

Blake D, Luke B, Kanellis P, Jorgensen P, Goh T, Penfold S, Breitkreutz BJ, Durocher D, Peter M, Tyers M,:  The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae. Genetics. 2006 Dec;174(4):1709-27. (see Abstract).


2005 and before

Kurz T, Ozlu N, Rudolf F, O’Rourke SM, Luke B, Hofmann K, Hyman AA, Bowermann B, Peter M: The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature. 2005 Jun 30;435(7046):1257-61. (see Abstract).

Gstaiger M, Luke B, Hess D, Oakeley EJ, Wirbelauer C, Blondel M, Vigneron M, Peter M, Krek W: Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. Science. 2003 Nov 14;302(5648):1208-12. (see Abstract).

*= equal contribution



Review


Luke B and Lingner J: TERRA: telomere repeat containing RNA. EMBO J. 2009 Sep 2;28(17):2503-10. Review (see Abstract).

Maicher A*, Kastner L*, and Luke B: Telomeres and Disease - Enter TERRA. RNA Biology. 2012, in Press.


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