Original Research Articles

Sandler H, Kreth J, Timmers HT, Stoecklin G. Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin. Nucleic Acids Res. 2011;39:4373-86.

Clement SL, Scheckel C, Stoecklin G, Lykke-Andersen J. Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment. Mol Cell Biol 2011;31:256-66.

Schott J, Stoecklin G. Networks controlling mRNA decay in the immune system. Wiley Interdiscip Rev RNA 2010;1:432-56.

Ozgur S, Chekulaeva M, Stoecklin G. Human Pat1b connects ceadenylation with RNA cecapping and controls the cssembly of processing bodies. Mol Cell Biol 2010;30:4308-23.

Stoecklin G, Tenenbaum SA, Mayo T, Chittur SV, George AD, Baroni TE, Blackshear PJ, Anderson P. Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin. J Biol Chem 2008;283:11689-99.

Yamasaki S, Stoecklin G, Kedersha N, Simarro M, Anderson P. T-cell intracellular antigen-1 (TIA-1)-induced translation silencing promotes the decay of selected mRNAs. J Biol Chem 2007; 282: 30070-7.

Stoecklin G, Yamasaki S, Stoecklin G, Kedersha N, Simarro M, Anderson P. T-cell intracellular antigen-1 (TIA-1)-induced translation silencing promotes the decay of selected mRNAs. J Biol Chem 2007; 282: 30070-7.

Sun L, Stoecklin G, Van Way S, Hinkovska-Galcheva V, Guo RF, Anderson P, Shanley TP. TTP/14-3-3 complex formation protects TTP from dephosphorylation by protein phosphatase 2A and stabilizes TNF-alpha mRNA. J Biol Chem 2007;282:3766-77.

Benjamin D, Colombi M, Stoecklin G, Moroni C. A GFP-based assay for monitoring post-transcriptional regulation of ARE-mRNA turnover. Mol Biosyst 2006;2:561-7.

Stoecklin G, Mayo T, Anderson P. ARE-mRNA degradation requires the 5'-3' decay pathway. EMBO Rep 2006;7:72-7.

Kedersha N, Stoecklin G, Ayodele M, Yacono P, Lykke-Andersen J, Fritzler MJ, Scheuner D, Kaufman RJ, Golan DE, Anderson P. Stress granules and Processing Bodies are dynamically linked sites of mRNP remodeling. J Cell Biol 2005;169:871-84.

Schmidlin M, Lu M, Leuenberger SA, Stoecklin G, Mallaun M, Gross B, Gherzi R, Hess D, Hemmings BA, Moroni C. The ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase B. EMBO J 2004;23:4760-69.

Gilks N, Kedersha N, Ayodele M, Shen L, Stoecklin G, Dember LM, Anderson P. Stress granule assembly is mediated by prion-like aggregation of TIA-1. Mol Biol Cell 2004;15:5383-98.

Stoecklin G, Stubbs T, Kedersha N, Wax S, Rigby WFC, Blackwell TK, Anderson P. MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J 2004, 23:1313-24.

Stoecklin G, Lu M, Rattenbacher B, Moroni C. A constitutive decay element promotes tumor necrosis factor alpha mRNA degradation via an AU-rich element-independent pathway. Mol Cell Biol 2003;23:3506-15.

Stoecklin G, Gross B, Ming XF, Moroni C. A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA. Oncogene 2003;22:3554-61.

Stoecklin G, Colombi M, Raineri I, Leuenberger S, Mallaun M, Schmidlin M, Gross B, Lu M, Kitamura T, Moroni C. Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover. EMBO J 2002;21:4709-18.

Chen CY, Gherzi R, Ong S, Chan E, Raijmakers R, Pruijn GJM, Stoecklin G, Moroni C, Mann M, Karin M. AU-binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell 2001;107:451-64.

Stoecklin G, Stoeckle P, Lu M, Muehlemann O, Moroni C. Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements. RNA 2001;7:1578-88.

Ming XF, Stoecklin G, Lu M, Looser R, Moroni C. Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase. Mol Cell Biol 2001;21:5778-89.

Stoecklin G, Ming XF, Looser R, Moroni C. Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway. Mol Cell Biol 2000;20:3753-63.

Stoecklin G, Hahn S, Moroni C. Functional hierarchy of AUUUA motifs in mediating rapid interleukin-3 mRNA decay. J Biol Chem 1994;269:28591-7.


Review Articles

Kulkarni M, Ozgur S, Stoecklin G. On track with P-bodies. Biochem Soc Trans 2010;38:242-51.

Sandler H, Stoecklin G. Control of mRNA decay by phosphorylation of tristetraprolin. Biochem Soc Trans 2008;36:491-6.

Stoecklin G, Anderson P. In a tight spot: ARE-mRNAs at processing bodies. Genes & Dev 2007;21:627-31.

Stoecklin G, Anderson P. Post-transcriptional mechanism regulating the inflammatory response. Adv Immunol 2006;89:1-37.

Newbury S, Muehlemann O and Stoecklin G. Turnover in the Alps: an mRNA perspective. EMBO Rep 2006;7:143-8.

Anderson P, Phillips K, Stoecklin G, Kedersha N. Posttranscriptional regulation of pro-inflammatory proteins. J Leuk Biol 2004;76:42-47.