Ruprecht-Karls-Universität Heidelberg

Publications by the Erhardt Lab

Search pubmed for publications by Sylvia Erhardt

Demerdizen E, Spiller-Becker M, Förtsch A, Wilhelm A, Bergner A, Bade D, Hessling B, Erhardt S.  Localization of Drosophila CENP-A to non-centromeric sites depends on the NuRD complex. Nucleic Acids Res. 2019 doi: 10.1093/nar/gkz962.


Pauleau A, Kajtez J, Bergner A, Erhardt S. Centromeric CENP-A loading requires accurate mitotic timing, which is linked to checkpoint proteins. PLoS Genet. 2019  doi: 10.1371/journal.pgen.1008380.


Lafarga V, Sung HM, Haneke K, Roessig L, Pauleau AL, Bruer M, Rodriguez-Acebes S, Lopez-Contreras A, Gruss OJ, Erhardt S, Mendez J, Fernandez-Capetillo F, Stoecklin G. TIAR marks nuclear G2/M transition granules and restricts CDK1 activity under replication stress. EMBO Rep 2019 Jan;20(1). pii: e46224. doi: 10.15252/embr.201846224. Epub 2018 Dec 11.


Pauleau AL, Bergner A, Kajtez J, Erhardt S. Centromeric CENP-A loading requires accurate mitotic timing, which is linked to checkpoint proteins. bioRxiv 2018 Sept 4. doi:


García Del Arco A, Edgar BA, Erhardt S. In vivo analysis of centromeric proteins reveals a stem cell-specific asymmetry and an essential role in differentiated, non-proliferating cells. Cell Rep. 2018 Feb 20;22(8):1982-1993.


Acharya S, Hartmann M, Erhardt S. Chromatin-associated noncoding RNAs in development and inheritance. Wiley Interdiscip Rev RNA. 2017 Aug 25. doi: 10.1002/wrna.1435. [Epub ahead of print] Review.


García Del Arco A, Erhardt S. Post-translational Modifications of Centromeric Chromatin. Prog Mol Subcell Biol. 2017;56:213-231. doi: 10.1007/978-3-319-58592-5_9.


Noetzold L, Frank L, Gandhi M, Polycarpou-Schwarz M, Groß M, Gunkel M, Beil N, Erfle H, Harder N, Rohr K, Trendel J, Krijgsveld J, Longerich T, Schirmacher P, Boutros M, Erhardt S, Diederichs S. The long non-coding RNA LINC00152 is essential for cell cycle progression though mitosis in HeLa cells.  Sci Rep. 2017 May 23;7(1):2265.


Bade D & Erhardt S. Book Chapter: Regulation of Centromeric chromatin, in ‘Chromatin
regulation and dynamics’ Elsivier 2016 (Editor: A. Göndör), eBook ISBN: 9780128034026


Rošic S & Erhardt S. No longer a nuisance: long non-coding RNAs join CENP-A in epigenetic centromere regulation. Cell Mol Life Sci. 2016 Apr;73(7):1387-98 Review


Rošic S, Köhler F, Erhardt S. Repetitive centromeric satellite RNA is essential for kinetochore formation and cell division. J. Cell Biol. 2014 Nov 10;207(3):335-49.


Mathew V, Pauleau AL, Steffen N, Bergner A, Becker PB, Erhardt S. The histone-fold protein CHRAC14 influenced chromatin composition in response to DNA damage. Cell Rep. 2014 Apr 24;7(2):321-30.


Bade D, Pauleau AL, Wendler A, Erhardt S. The E3 ligase CUL3/RDX controls centromere maintenance by ubiquitylating and stabilizing CENP-A in a CAL1-dependent manner. Dev Cell. 2014 Mar 10;28(5):508-19


Bade D, Erhardt, S.  Die Histonvariante CenH3 reguliert die Centromeridentität. Biospektrum 4/12 (2012). Review (non-peered reviewed), in German.


Pauleau, A, Erhardt S. Centromere regulation: new players, new rules, new questions.  Eur J Cell Biol. 2011 Oct;90(10):805-10 Review


Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo Copenhaver GP, DeLuca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LET, Karpen G, Kops GJPL, Lampson MA, S. M. Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh  AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O’Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT,  Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 2013 Apr;21(2):101-6. Review


Kappes F, Waldmann T, Mathew V, Yu J, Zhang L, Khodadoust MS, Chinnaiyan AM, Luger K, Erhardt S, Schneider R, Markovitz DM. The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity. Genes and Dev. 2011 Apr 1;25(7):673-8.


Erhardt S*, Mellone BG*, Betts CM*, Zhang W, Karpen GH, Straight AF. (*co-authors) Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagationJ. Cell Biol. 2008 Dec 1;183:805-818.


Mellone B, Erhardt S, Karpen GH. The ABCs of centromeres. Nat Cell Biol. 2006 May;8(5):427-9. News and Views.

Heun P*, Erhardt S*, Blower MD, Weiss S, Skora, AD, Karpen, GH. (*co-authors) Mislocalization of the Drosophila centromere-specific histone CID promotes formation of functional ectopic kinetochores.  Dev Cell. 2006 Mar 10; 303-315.


Hajkova P., Erhardt S., Surani MA. Epigenetic regulation of trophoblast development. Book chapter Biology And Pathology Of Trophoblast. (2006) Cambridge University Press (33-45).  Ashley Moffett, Anne McLaren, Charlie Loke (Editors).


Saitou M, Payer B, Lange UC, Erhardt S, Barton SC, Surani MA. Specification of germ cell fate in mice. Philos Trans R Soc Lond B Biol Sci. 2003 Aug 29;358(1436):1363 Review.


Erhardt S, Su IH, Schneider R, Barton S, Bannister AJ, Perez-Burgos L, Jenuwein T, Kouzarides T, Tarakhovsky A, Surani MA.  Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development. 2003 Sep 15;130(18):4235-4248.


Lane N, Dean W, Erhardt S, Hajkova P, Surani A, Walter J, Reik W.  Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis. 2003 Feb;35(2):88-93.


Erhardt S, Lyko F, Ainscough JFX, Surani MA, Paro R. Polycomb-Group proteins are involved in silencing processes caused by an element from the murine imprinted H19/Igf2 region in Drosophila Dev Genes Evol. 2003 Jul;213(7):336-44.


Arney KL, Erhardt S, Surani MA.  Genomic imprinting. Book chapter. Advances of developmental biology and biochemistry.  DePamphilis M (Editor), 2002; Vol 12, Elsevier Science: 234-264.


Hajkova P*, Erhardt S*, Lane N, Haaf T, El-Maarri O, Reik W, Walter J, Surani MA. (*co-authors). Epigenetic reprogramming in mouse primordial germ cells. Mech Dev. 2002 Sep;117(1-2):15-23.


Arney KL, Erhardt S, Drewell RA, Surani MA.  Epigenetic reprogramming of the genome--from the germ line to the embryo and back again. Int J Dev Biol. 2001;45(3 Spec No):533-40. Review.


O'Carroll D, Erhardt S, Pagani M, Barton SC, Surani MA, Jenuwein T. The polycomb-group gene Ezh2 is required for early mouse development. Mol Cell Biol. 2001 Jul;21(13):4330-6.

* co-authors

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