Journal articles and reviews

1) Back, S., Haas, P., Tschaepe, J.-A., Gruebl, T., Kirsch, J., Mueller, U., Beyreuther, K., Kins, S.#. In neurons APP can be transported independent of any sorting signal to the axonal and dendritic compartment. J. Neurosci. Res., in press.

2) Rusu, P., Jansen, A., Soba, P., Kirsch, J., Loewer, A., Merdes, G., Kuan, Y.-H., Jung, A., Beyreuther, K., Kjaerulff, O., Kins, S.#. Axonopathy in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity, Eur. J. Neurosci. 2007 Feb; 25 (4): 1079-86.

3) Kuan, Y.-H., Gruebl, T., Soba, P., Eggert, S., Nesic, I., Kirsch, J., Beyreuther, K., Kins, S.#. The processing and anterograde transport of APP, APLP1 and APLP2 is affected by the carboxyl-terminal binding partner PAT1a J. Biol. Chem., 2006, 281(52), 40114-123.

4) Kins, S.#, Lauther, N., Szodorai, A., and Beyreuther, K. Subcellular trafficking of the APP gene family and its pathogenic role in Alzheimer's Disease. Neurodegener Dis. 2006; 3 (4-5), 218-26.

5) Kins, S. #, Beyreuther, K. Teasing out the tangles. Nat. Med., 2006; 12(7), 764-5.

6) Goetz, J., Ittner, L.M., and Kins, S. Do axonal defects in tau and APP transgenic animals model axonopathy in Alzheimer's disease?, J. Neurochem., 2006; 98(4), 993-1006.

7) Horster F, Schwab MA, Sauer SW, Pietz J, Hoffmann GF, Okun JG, Kolker S, Kins S.# Phenylalanine reduces synaptic density in mixed cortical cultures from mice. Pediatr. Res., 2006; 59(4), 544-8.

8) Soba, P., Eggert, S., Wagner, K., Zentgraf, H., Siehl, K., Kreger, S., Lower, A., Langer, A., Merdes, G., Paro, R., Masters, C.L., Mueller, U., Kins, S.*, Beyreuther, K.* Cell interactions are promoted by trans-dimerization of APP family members, arranged as homo- or hetero-complexes in synaptic membranes. EMBO J., 2005, 24, 3624-36.

9) von Rotz, R.C.*, Kins, S.#*, Hipfel, R., von der Kammer, H., Nitsch, R.M. The cytosolic ring finger protein dactylidin is selectively upregulated in brains of patients with Alzheimer's disease. Eur. J. Neurosci. 2005, 21, 1289-98.

10) Lazarov, O., Morfini, G.A., Szodorai, A., Kins, S., Lee, V., Trojanowski, J., Price, D., Brady, S.T., Sisodia, S.S.  Axonal Transport, APP, Kinesin and the Processing Apparatus: Revisited. J. Neurosci. 2005, 25, 2386-95.

11) Kins, S., Kurosinski, P., Nitsch, R.M. and Goetz, J. Hyperphosphorylation and somatodendritic localization of tau in PP2A dominant negative mutant mice is associated with activation of ERK and JNK signaling. J. Am. Path., 2003, 163 (3), 833-843.

12) Schmidt, K.*, Kins, S.*, Schild, A., Nitsch, R.M., Hemmings, B. and Goetz, J. Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A. Eur. J. Neurosci., 2002, 16, 2039-48 (Imp. Factor 4,0).

13) Fuhrmann, J.C., Kins, S., Kirsch, J., Kneussel, M., Betz, H. Gephyrin interacts with DLC-1/PIN and DLC-2, components of the cytoplasmic dynein complex. J. Neurosci., 2002, 22, 5393-402.

14) Mueller, U. und Kins, S.# APP on the move. Trends Mol Med. 2002, 8, 152-5.

15) Steinhoff, T., Moritz, E., Wollmer, M. A., Mohajeri, M. H., Kins, S.# and Nitsch, R. M. Increased cystatin C in astrocytes of transgenic mice expressing the K670N-M671L mutation of the amyloid precursor protein and deposition in brain amyloid plaques.  Neurobiol Dis 2001, 8, 647-54.

16) Kins, S., Crameri, A., Evans, D. R., Hemmings, B. A., Nitsch, R. M., and Goetz, J. Reduced PP2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. J Biol Chem 2001, 276, 38193-200.

17) Grosskreutz, Y., Hermann, A., Kins, S., Fuhrmann, J. C., Betz, H., and Kneussel, M. Identification of a gephyrin-binding motif in the GDP/GTP exchange factor collybistin. Biol Chem 2000, 382, 1455-1462.

18) Ramming, M.*, Kins, S.*, Werner, N., Hermann, A., Betz, H., and Kirsch, J. Diversity and phylogeny of gephyrin: tissue-specific splice variants, gene structure, and sequence similarities to molybdenum cofactor-synthesizing and cytoskeleton-associated proteins. Proc Natl Acad Sci U S A 2000, 97, 10266-10271.

19) Kins, S., Betz, H., and Kirsch, J. Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin. Nat Neurosci 2000, 3, 22-29.

20) Kins, S., Kuhse, J., Laube, B., Betz, H. and Kirsch, J. Incorporation of a gephyrin-binding motif targets NMDA receptors to gephyrin-rich domains in HEK 293 cells. Eur. J. Neurosci. 1999, 11, 740-4.

*equal contribution

#corresponding author

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