Welcome to the Duarte Campos lab!

Bioprinting for tissue and organ engineering

Our lab investigates biofabrication technologies and bioinks suitable for tissue and organ engineering, and their impact on the structure and function of natural and synthetic living tissues.

Our goals

1. Study the impact of biofabrication technologies on cell growth and behaviour in 3D
2. Investigate synthetic alternatives to the human cell for tissue engineering applications
3. Develop biofabrication technologies and novel bioinks for in vitro, in situ and in vivo tissue and organ engineering
4. Design and investigate 3D models of human tissues in health and disease

Our projects

1. FauxLIFE: Bioprinting synthetic cells, Funding: Cluster of Excellence 3DMM2O
2. ORGAprint: Damage in organoids after bioprinting, Funding: Cluster of Excellence 3DMM2O
3. BlindZero: In vivo bioprinting keratoplasty, Funding: BMBF NanoMatFutur
4. LIGHTHEART: Surgical optogenetic bioprinting of engineered cardiac muscle, Funding: ERC StG

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Selected publications

2020

Duarte Campos DF*, Lindsay CD, Roth JG, LeSavage BL, Seymour AJ, Krajina BA, Ribeiro R, Costa P, Blaeser A, Heilshorn SC*. Bioprinting cell- and spheroid-loaded protein-engineered hydrogels as tissue-on-chip platforms. Front Bioeng Biotechnol 2020, doi.org/10.3389/fbioe.2020.00374

Duarte Campos DF*, De Laporte L*. Digitally fabricated and naturally augmented in vitro tissues. Adv Healthc Mater 2020, doi.org/10.1002/adhm.202001253

2019

Blaeser A, Heilshorn S, Duarte Campos DF*. Smart bioinks as de novo building blocks to bioengineer   living tissues. Gels 2019, doi.org/10.3390/gels5020029

Duarte Campos DF*, Zhang S, Kreimendahl F, Köpf M, Fischer H, Vogt M, Blaeser A, Apel C, Esteves-Oliveira M. Hand-held bioprinting for de novo vascular formation applicable to dental pulp regeneration. Connective Tissue Research 2019, doi: 10.1080/03008207.2019.1640217

Duarte Campos DF*, Rohde M, Ross M, Anvari P, Blaeser A, Vogt M, Panfil C, Yam GHF, Mehta JS, Fischer H, Walter P, Fuest M. Corneal bioprinting utilizing collagen-based bioinks and primary human keratocytes. J Biomed Mat Res Part A 2019, doi.org/10.1002/jbm.a.36702

2018

Betsch M, Cristian C, Lin YY, Blaeser A, Schöneberg J, Vogt M, Buhl E, Fischer H, Duarte Campos DF*. Incorporating 4D into bioprinting: Real-time magnetically directed collagen fiber alignment for generating complex multilayered tissues. Adv Healthc Mater 2018, doi.org/10.1002/adhm.201800894

* corresponding author