Ruprecht-Karls-Universität Heidelberg

Publications by the Gruss Lab


Search pubmed for publications by Oliver Gruss



Gruss OJ.
Nuclear transport receptor goes moonlighting, Nat Cell Biol, 12: 640-41 (2010)

Hearst SM, Gilder AS, Sandeep SN, Davis MD, George EM, Whittom AA, Toyota CG, Husedzinovic A, Gruss OJ, Herbert M.
Cajal body formatio
n correlates with differential coilin phosphorylation in primary and transformed cell lines, J Cell Sci, 122: 1872-81 (2009)

Reber S, Over S, Kronja I and Gruss OJ.
CaM kinase II Initiates meiotic spindle depolymerisation independently of APC/C activation, J Cell Biol. 183:1007-17 (2008)

Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J and Gruss OJ.
Eml3 is a nuclear microtubule binding protein required for proper alignment of chromosomes in metaphase. J Cell Sci. 121:1718-26. (2008)

Yokoyama H, Gruss OJ, Rybina S, Caudron M, Schelder M, Wilm M, Mattaj IW and Karsenti E.
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol. 180(5):867-75 (2008)

Petri S, Grimmler M, Over S, Fischer U, Gruss OJ.
Dephosphorylation of SMN by PPM1G/PP2Cγ governs Cajal body localization and stability of the SMN complex. J Cell Biol, 179(3):451-65 (2007)

Dumont J, Petri S, Pellegrin F, Terret ME, Bohnsack MT, Rassinier P, Georget V, Kalab P, Gruss OJ, and Verlhac MH.
A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes. J. Cell Biol. 176(3):295-305. (2007)

Godl K*, Gruss OJ*, Eickhoff J, Wissing J, Blencke S, Weber M, Degen H, Brehmer D, Orfi L, Horvath Z, Keri G, Muller S, Cotten M, Ullrich A, Daub H.
Proteomic characterization of the angiogenesis inhibitor SU6668 reveals multiple impacts on cellular kinase signaling. Cancer Res. 65(15):6919-26. (2005) *shared first authorship

Gruss OJ, Vernos I.
The mechanism of spindle assembly: functions of Ran and its target TPX2. J Cell Biol. Sep 27;166(7):949-55. (2004) Review.

Schatz CA, Santarella R, Hoenger A, Karsenti E, Mattaj IW, Gruss OJ*, Carazo-Salas RE*.
Importin alpha-regulated nucleation of microtubules by TPX2, EMBO J. 22: 2060-70. (2003) *shared last authorship

Gruss OJ*, Wittmann M*, Yokoyama H, Pepperkok R, Kufer TA, Silljé HHW, Karsenti E, Mattaj IW, Vernos I.
Chromosome-induced microtubule assembly mediated by TPX2 is required for spindle formation in HeLa cells, Nat Cell Biol., 4: 871-9. (2002) *
*shared first authorship

Hetzer M, Gruss OJ, Mattaj IW.
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly, Nat. Cell Biol. 4: E177-E184. (2002) Review

Kufer TA, Silljé HHW, Koerner R, Gruss OJ, Meraldi P, Nigg EA.
Human TPX2 is required for targeting Aurora-A kinase to the spindle. J. Cell Biol. 158: 617-23. (2002)

Carazo-Salas RE, Gruss OJ, Mattaj IW, Karsenti E.
Ran-GTP coordinates regulation of microtubule nucleation and dynamics during mitotic-spindle assembly. Nat Cell Biol. 3: 228-34. (2001)

Gruss OJ, Carazo-Salas RE, Schatz CA, Guarguaglini G, Kast J, Wilm M, Le Bot N, Vernos I, Karsenti E, Mattaj IW.
Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity. Cell 104: 83-93. (2001) *

Hetzer M, Bilbao-Cortes D, Walther TC, Gruss OJ, Mattaj IW.
GTP hydrolysis by Ran is required for nuclear envelope assembly. Mol. Cell 5:1013-24. (2000)

Carazo-Salas RE, Guarguaglini G, Gruss OJ, Segref A, Karsenti E, Mattaj IW.
Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation. Nature 400: 178-81. (1999)

Gruss OJ, Feick, P, Frank R, Dobberstein B.
Phosphorylation of components of the ER translocation site. Eur. J. Biochem. 260: 785-793. (1999).


* = equal contribution

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