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2022
Cerullo, F., Filbeck, S., Patil, P. R., Hung, H. C., Xu, H., Vornberger, J., Hofer, F. W., Schmitt, J., Kramer, G., Bukau, B., Hofmann, K., Pfeffer, S., & Joazeiro, C. A. P. (2022). Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue. Nature, 603(7901), 509–514.https://doi.org/10.1038/s41586-022-04487-6
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2021
Sharma, A.K., Venezian, J., Shiber, A., Kramer, G., Bukau, B., O´Brien E.P. Combinations of slow-translating codon clusters can increase mRNA half-life in Saccharomyces cerevisiae. (2021) Proc. Nat. Acad. Sci., 118: e2026362118. https://doi.org/10.1073/pnas.2026362118.
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2020
Wentink, A.S., Nillegoda, N.B., Feufel, J., Ubartaite, G., Schneider, C.P., De Los Rios, P., Hennig, J., Barducci, A., Bukau, B. Molecular dissection of amyloid disaggregation by the human Hsp70 chaperone. (2020) Nature, https://doi.org/10.1038/s41586-020-2904-6.
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Ahmed, N., Friedrich, U.A., Sormanni, P., Ciryam, P., Altman, N.S., Bukau, B., Kramer, G., O'Brien, E.P. Pairs of amino acids at the P- and A-sites of the ribosome predictably and causally modulate translation-elongation rates. (2020) J. Mol. Biol. S0022-2836(20)30614-8. doi: 10.1016/j.jmb.2020.10.030. Online ahead of print. (Abstract).
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Bohlen, J., Fenzl, K., Kramer, G., Bukau, B., Teleman, A.A. Selective 40S footprinting reveals cap-tethered ribosome scanning in human cells. (2020) Mol. Cell S1097-2765(20)30390-7. doi: 10.1016/j.molcel.2020.06.005. (Abstract).
den Brave F, Cairo L.V., Jagadeesan, C., Ruger-Herreros, C., Mogk, A., Bukau, B., Jentsch, S. Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions. (2020) Cell Rep. 31:107680. doi: 10.1016/j.celrep.2020.107680. PMID: 32492414. (Abstract).
Tittelmeier, J., Sandhof, C.A., Ries, H.M., Druffel-Augustin, S., Mogk, A., Bukau, B., Nussbaum-Krammer, C. The HSP110/HSP70 disaggregation system generates spreading-competent toxic alpha-synuclein species. (2020) EMBO J. 39:e103954. doi: 10.15252/embj.2019103954. (Abstract).
Avellaneda, M.J., Franke, K.B., Sunderlikova, V., Bukau, B., Mogk, A., Tans, S.J. Processive extrusion of polypeptide loops by a Hsp100 disaggregase. (2020) Nature, doi: 10.3390/ijms20246220. (Abstract).
2019
Castells-Ballester, J., Rinis, N., Kotan, I., Gal, L., Bausewein, D., Kats, I., Zatorska, E., Kramer, G., Bukau, B., Schuldiner, M., Strahl, S. Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation. (2019) Int. J. Mol.Sci. 20(24). pii: E6220. doi: 10.3390/ijms20246220. (Abstract).
Ho, C.-T., Grousl, T., Shatz, O., Jawed, A., Rutger-Herreros, C., Semmelink, M., Zahn, R., Richter, K., Bukau, B., Mogk, A. Cellular sequestrases maintain basal Hsp70 capacity ensuring balanced proteostasis. (2019) Nature Commun. 10:4851. doi: 10.1038/s41467-019-12868-1. (Abstract).
Rusu, P., Shao, C., Neuerburg, A., Acikgöz, A.A., Wu, Y., Zou, P., Phapale, P., Shankar, T.S., Döring, K., Dettling, S., Körkel-Qu, H., Bekki, G., Costa, B., Guo, T., Friesen, O., Schlotter, M., Heikenwalder, M., Tschaharganeh. D.F., Bukau, B., Kramer, G., Angel, P., Herold-Mende, C., Radlwimmer, B., Liu, H.K. GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile. (2019) Cell Stem Cells pii: S1934-5909(19)30268-1. doi: 10.1016/j.stem.2019.06.004. (Abstract).
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Jamshad, M., Knowles, T.J., White, S.A., Ward, D.G., Mohammed, F., Rahman, K.F., Wynne, M., Hughes, G.W., Kramer, G., Bukau, B., Huber, D. The C-terminal tail of the bacterial translocation ATPase SecA modulates its activity. (2019) Elife pii: e48385. doi: 10.7554/eLife.48385 (Abstract).
Deville, C., Franke, K., Mogk, A., Bukau, B., Saibil, H.R. Two-Step Activation Mechanism of the ClpB Disaggregase for Sequential Substrate Threading by the Main ATPase Motor. (2019) Cell Rep. pii: e48385. doi: 10.7554/eLife.48385 (Abstract).
Maurer, M., Linder, D., Franke, K.B., Jäger, J., Taylor, G., Gloge, F., Gremer, S., Le Breton, L., Mayer, M.P., Weber-Ban, E., Carroni, M., Bukau, B., Mogk, A. Toxic Activation of an AAA+ Protease by the Antibacterial Drug Cyclomarin A. (2019) Cell Chem. Biol., pii: S2451-9456(19)30177-1. doi: 10.1016/j.chembiol.2019.05.008 (Abstract).
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2018
Kramer, G., Shiber, A., Bukau, B. Mechanisms of Co-Translational Maturation of Newly Synthesized Proteins. (2018) Ann. Rev. Biochem., doi: 10.1146/annurev-biochem-013118-111717 (Abstract).
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Lee, C., Franke, K.B., Kamal, S.M., Kim, H., Lünsdorf, H., Jäger, J., Nimtz, M., Trcek, J., Jänsch, L., Bukau, B., Mogk, A., Römling, U. Stand-alone ClpG disaggregase confers superior heat tolerance to bacteria. (2018) Proc. Natl. Acad. Sci. USA 115:E273-E282. doi: 10.1073/pnas.1712051115. (Abstract).
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2017
Carroni, M., Franke, K.B., Maurer, M., Jäger, J., Hantke, I., Gloge, F., Linder, D., Gremer, S., Turgay, K., Bukau, B., Mogk, A. Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control. (2017) Elife pii: e30120. doi: 10.7554/eLife.30120. (Abstract).
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Acosta-Sampson, L., Döring, K., Lin, Y., Yu, V.Y., Bukau, B., Kramer, G., Cate, J.H.D. Role for Ribosome-Associated Complex and Stress-Seventy subfamily B (RAC-Ssb) in integral membrane protein translation. (2017) J. Biol. Chem. pii: jbc.M117.813857. doi: 10.1074/jbc.M117.813857. (Abstract).
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Zemva, J., Fink, C.A., Fleming, T.H., Schmidt, L., Loft, A., Herzig, S., Knieß, R.A., Mayer, M., Bukau, B., Nawroth, P.P., Tyedmers, J. Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux. (2017) Redox Biol. 13:674-686. doi: 10.1016/j.redox.2017.08.007. (Abstract).
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Bascos, N.A.D., Mayer, M.P., Bukau, B., Landry, S.J. The Hsp40 J-domain modulates Hsp70 conformation and ATPase activity with a semi-elliptical spring. (2017) Protein Sci. doi: 10.1002/pro.3223 (Epub ahead of print). (Abstract).
Garcia, V.M., Nillegoda, N.B., Bukau, B., Morano, K.A. Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone, Sse1, is not obligate for its biological activities. (2017) Mol. Biol. Cell pii: mbc.E17-01-0070. doi: 10.1091/mbc.E17-01-0070. Epub ahead of print. (Abstract).
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2016
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2015
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2014
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2013
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2012
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2011
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