Ruprecht-Karls-Universität Heidelberg
Publications by the Joazeiro Lab

Search pubmed for publications by Claudio Joazeiro

Cerullo, F., Filbeck, S., Patil, P.R., Hung, H.-C., Xu, H., Vornberger, J., Hofer, F., Schmitt, J., Kramer, G., Bukau, B., Hofmann, K., Pfeffer, S. and Joazeiro, C. 2022. Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue. Nature 603:509-514 


Filbeck, S., Cerullo, F., Pfeffer, S. and Joazeiro, C. 2022. Ribosome-associated Quality Control (RQC) Mechanisms from Bacteria to Humans. Mol. Cell 82:1451-1466 


Thrun, A., Garzia, A., Kigoshi-Tansho, Y., Patil, P., Umbaugh, C., Dallinger, T., Liu, J., Kreger, S., Patrizi, A., Cox, G., Tuschl, T. and Joazeiro, C. 2021. Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing. Mol. Cell 81:2112-2122 


Filbeck, S., Cerullo, F., Paternoga, H., Tsaprailis, G., Joazeiro, C.* and Pfeffer S.* 2021. Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC. Mol. Cell 81:104-114 * co-senior authors • featured under “Preview” in Mol. Cell 2021, 81:6-7 


Martin, P., Kigoshi-Tansho, Y., Sher, R., Ravenscroft, G., Stauffer, J.E., Kumar, R., Yonashiro, R., Müller, T., Griffith, C., Allen, W., Pehlivan, D., Haral, T., Zenker, M., Howting, D., Schanze, D., Faqeih, E., Almontashiri, N., Maroofian, R., Houlden, H., Mazaheri, N., Galehdari, H., Douglas, G., Posey, J.E., Ryan, M., Lupski, J.R., Laing, N.G., Joazeiro, C.* and Cox, G.* 2020. NEMF mutations that impair ribosome-associated quality control are associated with neuromuscular disease. Nature Comm. 11:5022. * co-senior authors 


Lytvynenko, I., Paternoga, H., Thrun, A., Balke, A., Müller, T., Chiang, C., Nagler, K., Tsaprailis, G., Anders, S., Bischofs, I., Maupin-Furlow, J., Spahn, C., Joazeiro, C. 2019. Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control. Cell 178:76-90 


Joazeiro, C. 2019. Mechanisms and functions of ribosome-associated protein quality control. Nat. Rev. Mol. Cell Biol. 20:368-383Joazeiro, C.A.P. 2017. Ribosomal Stallinh During Translation: Providing Substrates for Ribosome-Associated Protein Quality Control. Annu Rev Cell Dev Biol. 33:343-368


Doamekpor, S., Lee, J., Hepowit, N., Wu, C., Charenton, C., Leonard, M., Bengtson, M., Rajashankar, K., Sachs, M., Lima, C. and Joazeiro C.A.P. 2016. Structure and function of the yeast listerin (Ltn1) conserved N-terminal domain in binding to stalled 60S ribosomal subunits. Proc Natl Acad Sci USA 113(29):E4151-60


Yonashiro, R., Tahara, E., Bengtson, M., Khokhrina, M., Lorenz, H., Chen, K., Kigoshi-Tansho, Y., Savas, J., Yates, J., Kay, S., Craig, E., Mogk, A., Bukau, B. and Joazeiro, C.A.P. 2016. The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation. eLife 5:e11794

Satoh, T., Sumiyoshi, A., Yagi-Utsumi, M., Sakata, E., Sasakawa, H., Kurimoto, E., Yamaguchi, Y., Li, W., Joazeiro, C.A., Hirokawa, T. and Kato, K. 2014. Mode of substrate recognition by the Josephin domain of ataxin-3, which has an endotype deubiquitinase activity. FEBS Lett. 588(23):4422-30

Lyumkis, D., dos Passos, D.O., Tahara, E., Bennett, E., Vinterbo, S., Potter, C.S., Carragher, B. and Joazeiro, C.A.P. 2014. Structural Basis for Translational Surveillance by the Large Ribosomal Subunit-Associated Protein Quality Control Complex. Proc. Natl. Acad. Sci. USA 111:15981-6

Ossareh-Nazari, B., Niño, C.A., Bengtson, M.H., Lee, J.-W., Joazeiro, C.A.P. and Dargemont, C. 2014. Ubiquitylation by the Ltn1 E3 ligase protects 60S ribosomes from starvation-induced selective autophagy. J. Cell Biol. 204:909-919

Lyumkis, D., Doamekpor, S., Bengtson, M., Lee, J., Toro, T., Petroski, M., Lima, C., Potter, C., Carragher, B. and Joazeiro, C.A.P. 2013. Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase. Proc Natl Acad Sci USA 110(5):1702-7

Mitne-Neto, M., Machado-Costa, M., Marchetto, M.C., Bengtson M., Joazeiro C.A.P., Tsuda H., Bellen H., Silva H., Oliveira A., Lazar M., Muotri A. and Zatz M. 2011. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stm cells of ALS8 patients. Hum Mol Genet 15;20(18):3642-52

Bengtson, M.H. and Joazeiro, C.A.P. 2010. Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467:470-473

Chu, J., Hong, N., Masuda, C., Jenkins, B., Nelms, K., Goodnow, C., Glynne, R., Wu, H., Masliah, E., Joazeiro, C.A.P. and Kay, S.A. 2009. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. Proc. Natl. Acad. Sci. USA 106:2097-2103

Deshaies, R.J. and Joazeiro, C.A.P. 2009. RING Domain E3 Ubiquitin Ligases. Ann. Rev. Biochem. vol. 78: 399-434

Li, W., Bengtson, M., Ulbrich, A., Matsuda, A., Orth, A., Chanda, S., Batalov, S. and Joazeiro, C.A.P. 2008. Genome-wide and Functional Annotation of Human E3 Ubiquitin Ligases Identifies MULAN, a Mitochondrial E3 that Regulates the Organelle’s Dynamics and Signaling. PLoS ONE 3:e1487

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