MCB Module 3

The MCB Curriculum - Module 3

Module 3 consists of three parts:

1) The lecture series 'Advanced Molecular & Cellular Biology' which covers topics like (subject to change):
Biosensors
Deep Learning models of the cis-regulatory code
DNA Assembly and Synthetic Genomics
Drosophila as a model system
Introduction to Translational Research
Mass spectrometry
Medicinal Chemistry / Drug Discovery
Methods to study protein folding
Organoids and other 3D stem cell models
Protein Modeling
qPCR
Ribosome Profiling
RNA origami
Spatial Biology - Technologies and Analysis
Structural biology using cryo-electron microscopy
Target Validation / Drug Discovery
Visualizing and dissecting mammalian gene expression

In the end there will be an exam.

2) three one-week practicals, which you can choose from a large list of topics, including (subject to change):
- 3D cell culture, cell viability, tissue engineering
- Characterisation of novel regulators in cell signalling
- Components and mechanisms of signal transduction
- Electron Microscopy in Parasitology: Unraveling the Malaria Pathogen
- Hands-on bioprinting basics - bioprinting, hydrogels
- Introduction to Epigenome profiling (wet & dry)
- Introduction to Python for life scientists
- Mass spectrometry
- MCB in translational cancer research?
- Molecular and cellular biology of endospores / Bacterial signaling networks
- Monitoring protein interactions by crosslinking and fluorescent measurements
- Neonatal rat cardiomyocytes
- Next generation sequencing for clinical testing in cardiovascular diseases
- Organoid handling and imaging
- phytochrome-B Nuclear bodies and light signalling
- Purification and analysis of the Ribosome-Associated Quality Control (RQC) complex
- RNA Single Cell Seq
- Structural biology
- Structure and biochemistry of RNA and protein-RNA complexes
- Techniques for engineering synthetic cells
- Translational control in cardiomyocytes.

3) a separate literature seminar.