Ruprecht-Karls-Universität Heidelberg

Publications by the Schiebel Lab

Search pubmed for publications by Elmar Schiebel

Original articles


Theile, L., Li, X., Dang, H., Mersch, D., Anders, S., and Schiebel, E. (2023). Centrosome linker diversity and its function in centrosome clustering and mitotic spindle formation. EMBO J., 2023 Jul 4 e109738. doi: 10.15252/embj.2021109738.


Partscht, P., Simon, A., Chen, N.-P., Erhardt, S., and E. Schiebel. (2023). The HIPK2/CDC14B-MeCP2 axis enhances the spindle assembly checkpoint block by promoting cyclin B translation. Sci Adv. 2023 Jan 20;9(3). doi: 10.1126/sciadv.add6982.


Zupa, E., Würtz, M., Neuner, A., Hoffmann, T., Rettel, M., Böhler, A., Vermeulen, B.J.A., Eustermann, S., Schiebel, E., and Pfeffer, S. (2023). The augmin complex architecture reveals structural insights into microtubule branching. Nat Commun. 2022 Sep 26;13(1). doi: 10.1038/s41467-022-33228-6. 


Karasu, O.K.,  A. Neuner, E.S. Atorino, G. Pereira, and E. Schiebel. (2022). The central scaffold protein CEP350 coordinates centriole length, stability and maturation. J. Cell Biol., doi: 10.1083/jcb.202203081.


Dang, H., A. Martin-Villalba, and E. Schiebel. (2022). Centrosome linker protein C-Nap1 maintains stem cells in mouse testes. EMBO Rep., doi: 10.15252/embr.202153805.


Vitale, J., A. Khan, A. Neuner, and E. Schiebel. (2022). A perinuclear alpha-helix with amphipathic features in  Brl1 promotes NPC assembly. Mol. Biol. Cell, May 1;33(5):ar35. doi: 10.1091/mbc.E21-12-0616. Epub 2022 Mar 16.


Würtz, M., E. Zupa, E.S. Atorino, A. Neuner, A. Böhler, A.S. Rahadian, B.J.A. Vermeulen, G. Tonon, S. Eustermann, E. Schiebel, and S. Pfeffer. (2022). Modular assembly of the principal microtubule nucleator gamma-TuRC. Nat. Commun. 13(1): 473. doi: 10.1038/s41467-022-28079-0.


Zhang, W., A. Khan, J. Vitale, A. Neuner, K. Rink, C. Lüchtenborg, B. Brügger, T. H. Söllner, and E. Schiebel. (2021). A short perinuclear amphipathic alpha-helix in Apq12 promotes nuclear pore complex biogenesis. Open Biology,


Böhler, A., B.J.A. Vermeulen, M. Würtz, E. Zupa,, S. Pfeffer, and E. Schiebel. (2021). The gamma-tubulin ring complex: Deciphering the molecular organization and assembly mechanism of a major vertebrate microtubule nucleator. BioEssays,


Würtz, M., A. Böhler, A. Neuner, E. Zupa, L. Rohland, P. Liu, B. J.A. Vermeulen, S. Pfeffer, S. Eustermann, and E. Schiebel. (2021). Reconstitution of the recombinant human γ-tubulin ring complex. Open Biology, Published:03 February 2021


Rüthnick, D., J. Vitale, A. Neuner, and E. Schiebel. (2021). The N-terminus of Sfi1 and yeast centrin Cdc31 provide the assembly site for a new spindle pole body. J. Cell Biol. 220(3): e202004196.


Partscht, P., B. Uddin, and E. Schiebel. (2021). Human cells lacking CDC14A and CDC14B show differences in ciliogenesis but not in mitotic progression. J. Cell Sci, Jan 27;134(2):jcs255950. doi: 10.1242/jcs.255950.


Atorino, E.S., S. Hata, C. Funaya, A. Neuner, A., and E. Schiebel. (2020). CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion. Nat Comm, Feb 14;11(1):903. doi: 10.1038/s41467-020-14767-2.


Liu, P., M. Würtz, E. Zupa, S. Pfeffer, and E. Schiebel. (2020). Microtubule nucleation: The waltz between gamma-tubulin ring complex and associated proteins. Curr. Opin. Cell Biol. 68:124-131.


Zupa, E., P. Liu, M. Würtz, E. Schiebel, and S. Pfeffer. (2020). The structure of the γ-TuRC: a 25-years-old molecular puzzle. Curr. Opin. Struct. Biol. 66:15-21.


Liu, P., E. Zupa, A. Neuner, A. Böhler, J. Loerke, D. Flemming, T. Ruppert, T. Rudack, C. Peter, C. Spahn, O.J. Gruss, S. Pfeffer*, and E. Schiebel*. (2019). Insights into the assembly and activation of the microtubule nucleator gamma-TuRC. Nature, doi: 10.1038/s41586-019-1896-6. [Epub ahead of print]. * Co-corresponding authors.


Hata, S.*, A. Pastor Peidro, M. Panic, P. Liu, E. Atorino, C. Funaya, U. Jaekle, G. Pereira, and E. Schiebel*. (2019). The balance between KIFC3 and EG5 tetrameric kinesins controls the onset of mitotic spindle assembly. Nat. Cell Biol., 21:1138-1151. * Co-corresponding authors.


Uddin, B., P. Partscht, N.-P. Chen, A. Neuner, M. Weiß, R. Hardt, A.J. Pour, B. Heßling, T. Ruppert, H. Lorenz, G. Pereira*, and E. Schiebel*. (2018). The human phosphatase CDC14A modulates primary cilium length by regulating centrosomal actin nucleation. EMBO Rep., 2018 Nov 22. pii: e46544. doi: 10.15252/embr.201846544. [Epub ahead of print].* Co-corresponding authors.


Gunzelmann, J., D. Rüthnick, T.C. Lin, W. Zhang, A. Neuner, U. Jäkle, and E. Schiebel. (2018). The microtubule polymerase Stu2 promotes oligomerization of the gamma-TuSC for cytoplasmic microtubule nucleation. eLife, 2018 Sep 17; 7. pii: e39932. doi: 10.7554/eLife.39932.


Vodicska, B., B. Cerikan, E. Schiebel, and Ingrid Hoffmann. (2018). MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression. Scientific Reports, 8:6330.


Vlijm, R., X. Li, M. Panic, D. Rüthnick, S. Hata, F. Herrmannsdörfer, T. Kuner, M. Heileman, J. Engelhardt, S.W. Hell*, and E. Schiebel*. (2018). STED nanoscopy of the centrosome linker reveals a CEP68-organised, periodic rootletin network anchored to a C-Nap1 ring at centrioles. Proc. Nat. Acad. Sci. USA, 2018 Febr. 20. [Epub ahead of print].* Co-corresponding authors.


Zhang, W., A. Neuner, D. Rüthnick, T. Sachsenheimer, C. Lüchtenborg, B. Brügger, and E. Schiebel. (2018). Brr6 and Brl1 locate to nuclear pore complex assembly sites to promote their biogenesis. J. Cell Biol., 217:877-894.


Maekawa, H., A. Neuner, D. Rüthnick, E. Schiebel, G. Pereira, and Y. Kaneko. (2017). Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha. eLife, 6:e24340.


Rüthnick, D., A. Neuner, F. Dietrich, D. Kirrmaier, U. Engel, M. Knop, and E. Schiebel. (2017). Characterization of spindle pole duplication reveals a regulatory role for NPCs. J. Cell Biol., 216:2425-2442.


Chen, N.-P., B. Uddin, R. Hardt, W. Ding, M. Panic, I. Lucibello, P. Kammerer, T. Ruppert, and E. Schiebel. (2017). Human phosphatase CDC14A regulates actin organization through dephosphorylation of epithelial protein lost in neoplasm. Proc. Natl. Acad. Sci. USA, 114:5201-5206.


Kupke, T., J. Malsam and E. Schiebel. (2017). A ternary membrane protein complex anchors the spindle pole body in the nuclear envelope in budding yeast. J. Biol. Chem., 292:8447-8458.


Cerikan, B. and E. Schiebel. (2017). Mechanism of cell-intrinsic adaptation to Adams-Oliver Syndrome gene DOCK6 disruption highlights ubiquitin-like modifier ISG15 as a regulator of RHO GTPases. Small GTPases, 2017 Feb 23:1-8.


Lin, T., A. Neuner, D. Flemming, P. Liu, T. Chinen, U. Jaekle, R. Arkowitz, and E. Schiebel. (2016). MOZART1 and gamma-tubulin complex receptors are both required to turn gamma-TuSC into an active microtubule nucleation template. J. Cell Biol., 215:823-840.


Cerikan, B., R. Shaheen, G. P. Colo, C. Gläßer, S. Hata, K.-P. Knobeloch, F. S. Alkuraya, R. Fässler, and E. Schiebel. (2016). Cell intrinsic adaptation arising from chronic ablation of a key Rho GTPase regulator. Dev. Cell, 39:28-43.


Agircan F.G., S. Hata, C. Nussbaum-Krammer, E.S. Atorino, and E. Schiebel. (2016). Proximity mapping of human separase by the BioID approach. Biochem. Biophys. Res. Comm., epub: doi:10.1016/j.bbrc.2016.08.002.


Chen, N.-P., B. Uddin, R. Voit, and E. Schiebel. (2016). Human phosphatase CDC14A is recruited to the cell leading edge to regulate cell migration and adhesion. Proc. Natl. Acad. Sci. USA, 113:990-995.


Stankovic-Valentin, N., K. Drzewicka, C. König, E. Schiebel, and F. Melchior. (2016). Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress. EMBO J., pii: e201593404.


Uddin, B., N.-P. Chen, M. Panic, and E. Schiebel. (2015). Genome editing through large insertion leads to the skipping of targeted exon. BMC Genomics, 16:1082. doi:10.1186/s12864-015-2284-8.


Chinen, T., P. Liu, S. Shioda, J. Pagel, B. Cerikan, T. Lin, O. Gruss, Y. Hayashi, H. Takeno, T. Shima, Y. Okada, I. Hayakawa, Y. Hayashi, H. Kigoshi, T. Usui* and E. Schiebel*. (2015). The gamma-tubulin specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle. Nat. Commun., 6:8722. doi: 10.1038/ncomms9722. * Co-corresponding authors.


Seybold, C., M. Elserafy, D. Rüthnick, M. Ozboyaci, A. Neuner, B. Flottmann, M. Heilemann,, R.C. Wade, and E. Schiebel. (2015). Kar1 binding to Sfi1 C-terminal regions anchors the SPB bridge to the nuclear envelope. J. Cell Biol., 209:843-861.


Panic, M., S. Hata, A. Neuner and E. Schiebel. (2015). The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes. PlosGenetics, May 22;11(5):e1005243. doi:10.1371/journal.pgen.1005243. eCollection 2015 May.


Miller, S.B.M., C. Ho, J. Winkler, M. Khokhrina, A.Neuner, M. Y. H. Mohamed, D.L. Guilbride, K. Richter, M. Lisby, E. Schiebel, A. Mogk and B. Bukau. (2015). Compartment-specific aggregases direct distinct nuclear and cytoplasmic aggregate deposition. EMBO J., 34:778-797.


Agircan, F.G. and E. Schiebel. (2014). Sensors at centrosomes reveal determinants of local separase activity. PLoSGenetics, 10:e1004672.doi: 10.1371/journal.pgen.1004672. eCollection 2014 Oct.


Elserafy, M., M. Saric, A. Neuner, T. Lin, W. Zhang, C. Seybold, L. Sivashanmugam, and E. Schiebel. (2014). Molecular mechanisms that restrict yeast centrosome duplication to one event per cell cycle. Curr. Biol., 24:1456-1466.


Lin, T., A. Neuner, Y. Schlosser, A. Scharf, L. Weber, and E. Schiebel. (2014). Cell-cycle dependent phosphorylation of yeast pericentrin regulates gamma-TuSC-mediated microtubule nucleation. eLife, 3:e02208 (DOI:


Gombos, L., A. Neuner, M. Berynskyy, L.L. Fava, R.C. Wade, C. Sachse, and E. Schiebel. (2013). GTP regulates the microtubule nucleation activity of gammal-tubulin. Nature Cell Biol., 15:1317-1327.


Mardin, B. R., M. Isokane, M. R. Cosenza, A. Krämer, J. Ellenberg, A. M. Fry, and E. Schiebel. (2013). EGF induced centrosome separation promotes mitotic progression and cell survival. Dev. Cell., 25:229-240.

Khmelinskii, A., P.J. Keller, A. Bartosik, M. Meurer, J.D. Barry, B.R. Mardin, A. Kaufmann, S. Trautmann, M. Wachsmuth, G. Pereira, W. Huber, E. Schiebel*, and M. Knop*. (2012). Tandem fluorescent protein timers for in vivo analysis of protein dynamics. Nat. Biotechnol., 30:708-714. * Co-corresponding authors.

Erlemann, S., A. Neuner, L. Gombos, R. Gibeaux, C. Antony, and E. Schiebel. (2012). An extended gamma-tubulin ring functions as a stable platform in microtubule nucleation. J. Cell Biol., 197:59-74.

Florindo, C., J. Perdigao, D. Fesquet, E. Schiebel, J. Pines, and A. A. Tavares. (2012). Human Mob1 proteins are required for cytokinesis by controlling microtubule stability. J. Cell Sci., 125:3085-3090.

Luconi, L., Y. Araki, S. Erlemann, and E. Schiebel. (2011). The CENP-A chaperone Scm3 becomes enriched at kinetochores in anaphase independently of CENP-A incorporation. Cell Cycle, 10:3369-3378.

Kupke, T., L. Di Cecco, H.-M. Mueller, A. Neuner, F. Adolf, F. Wieland, W. Nickel, and E. Schiebel. (2011). Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication. EMBO J., 30:3337-3352.

Mardin, B.R., F.G. Agircan, C. Lange, and E. Schiebel. (2011). Plk1 controls the Nek2A-PP1gamma antagonism in centrosome disjunction. Curr. Biol., 21:1145-1151.

Lin, T., L. Gombos, A. Neuner, D. Sebastian, J.V. Olsen, A. Hrle, C. Benda, and E. Schiebel. (2011). Phosphorylation of the yeast gamma-tubulin Tub4 regulates microtubule function. PLOSone, 6:e19700.

Roostalu, J., C. Hentrich, P. Bieling, I.A. Telley, E. Schiebel*, and T. Surrey*. (2011). Directional switching of the kinesin Cin8 through motor coupling. Science, 332:94-99. * Co-corresponding authors.

Khmelinskii, A., M. Meurer, M. Knop* and E. Schiebel*. (2011). Artificial tethering to nuclear pores promotes partitioning of extrachromosomal DNA during yeast asymmetric cell division. Curr. Biol., 21:R17-18. * Co-corresponding authors.

Mardin, B.R., C. Lange, J.E. Baxter, T. Hardy, S.R. Scholz, A.M. Fry and E. Schiebel (2010). Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction. Nature Cell Biol., 12:1166-1176.

Khmelinskii, A., P.J. Keller, H. Lorenz, E. Schiebel* and M. Knop*. (2010). Segregation of yeast nuclear pores. Nature, 466(7305):E1. * Co-corresponding authors.

Mocciaro, A., E. Berdougo, K. Zeng, E. Black, P. Vagnarelli, W. Earnshaw, D. Gillespie, P. Jallepalli* and E. Schiebel*. (2010). Cells deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired for DNA repair. J. Cell Biol., 189:631-639. * Co-corresponding authors.

Araki, Y., L. Gombos, S.P.S. Migueleti, L. Sivashanmugam, C. Antony and E. Schiebel. (2010). N-terminal regions of Mps1 kinase determine functional bifurcation. J. Cell Biol., 189:41-56.

König, C., H. Maekawa and E. Schiebel. (2010). Mutual regulation of cyclin dependent kinase and the mitotic exit network. J. Cell Biol., 188:351-368.

Khmelinskii, A., J. Roostalu, H. Roque, C. Antony and E. Schiebel. (2009). Phosphorylation-dependent protein interactions at the spindle midzone mediate cell cycle regulation of spindle elongation. Dev. Cell, 17:244-256.

Sezen, B., M. Seedorf and E. Schiebel. (2009). The SESA network links duplication of the yeast centrosome with the protein translation machinery. Genes Dev., 23:1559-1570.

Maekawa., H., C. Priest, J. Lechner, G. Pereira* and E. Schiebel*. (2007). The yeast centrosome translates the positional information of the anaphase spindle into a cell cycle signal. J. Cell Biol., 179:423-436. * Co-corresponding authors.

Vernarecci, S., G. Colotti, P. Ornaghi, E. Schiebel, E. Chiancone and P. Filetici. (2007). The yeast Penta-EF protein Pef1p is involved in cation dependent budding and cell polarization. Mol. Microbiol., 65:1122-1138.

Khmelinskii, A., C. Lawrence, J. Roostalu and E. Schiebel. (2007). Cdc14-regulated midzone assembly controls anaphase B. J. Cell Biol., 177:981-993.

Araki, Y., C.K. Lau, H. Maekawa, S.L. Jaspersen, T.H. Giddings, Jr., E. Schiebel and M. Winey. (2006). The Saccharomyces cerevisiae spindle pole body component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p. Mol. Biol. Cell, 17:1959-1970.

Pereira, G.* and E. Schiebel*. (2005). Kin4 kinase delays mitotic exit in response to spindle alignment defects. Mol. Cell, 19:209-221. * Co-corresponding authors.

Fischer, T., S. Rodríguez-Navarro, G. Pereira, A. Rácz, E. Schiebel and E. Hurt. (2004). Yeast centrin Cdc31 is linked to the nuclear mRNA export machinery. Nature Cell Biol., 6:840-848.

Maekawa, H. and E. Schiebel. (2004). Cdk1-Clb4 controls the interaction of astral microtubule plus ends with sub-domains of the daughter cell cortex. Genes Dev., 18:1709-1724.

Janke, C., M. Magiera, N. Rathfelder, C. Taxis, S. Reber, H. Maekawa, A. Moreno-Borchart, G. Doenges, E. Schwob, E. Schiebel and M. Knop. (2004). A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes. Yeast, 21:947-962.

Höfken, T. and E. Schiebel. (2004). Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2. J. Cell Biol., 164: 219-231.

Scharfenberger, M., J. Ortiz, N. Grau, C. Janke, E. Schiebel and J. Lechner (2003). Nsl1p, a novel component of the S. cerevisiae kinetochore, is essential for the establishment of bipolarity and kinetochore localization of the Dam-Duo complex. EMBO J., 22: 6584-6597.

Pereira, G.* and E. Schiebel*. (2003). Separase regulates INCENP-Aurora B anaphase spindle function through Cdc14. Science, 302: 2120-2124. * Co-corresponding authors.

Usui, T., H. Maekawa, G. Pereira and E. Schiebel. (2003). The XMAP215 homologue Stu2 at yeast spindle pole bodies regulates microtubule dynamics and anchorage. EMBO J., 22: 4779-4793.

Maekawa, H., T. Usui, M. Knop and E. Schiebel. (2003). Yeast Cdk1 translocates to the plus end of cytoplasmic microtubules to regulate bud cortex interactions. EMBO J., 22: 438-449.

Höfken, T. and E. Schiebel. (2002). A role for cell polarity proteins in mitotic exit. EMBO J., 21: 4851-4862.

Pereira, G., C. Manson, J. Grindlay and E. Schiebel. (2002). Regulation of the Bfa1p-Bub2p complex at spindle pole bodies by the cell cycle phosphatase Cdc14p. J. Cell Biol., 157: 367-379.

Tanaka, T.U., N. Rachidi, C. Janke, G. Pereira, M. Galova, E. Schiebel, M.J.R. Stark and K. Nasmyth. (2002). Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections. Cell, 108: 317-329.

Janke, C., J. Ortíz, T.U. Tanaka, J. Lechner and E. Schiebel. (2002). Four new subunits of the Dam1-Duo1 complex reveal novel functions in sister kinetochore biorientation. EMBO J., 21: 181-193.

Pereira, G., T.U. Tanaka, K. Nasmyth and E. Schiebel. (2001). Modes of spindle pole body inheritance and segregation of the Bfa1p/Bub2p checkpoint protein complex. EMBO J., 20: 6359-6370.

Schramm, C., C. Janke and E. Schiebel. (2001). Molecular dissection of yeast spindle pole bodies by two hybrid, in vitro binding, and co-purification. Meth. Cell Biol., 67: 71-94.

Janke, C., J. Ortíz, J. Lechner, A. Shevchenko, A. Shevchenko, M. M. Magiera, C. Schramm and E. Schiebel. (2001). The budding yeast Spc24p and Spc25p interact with Ndc80p and Nuf2p at the kinetochore and are important for kinetochore clustering and checkpoint control. EMBO J., 20: 777-791.

Gruneberg, U., K. Campbell, C., Simpson, J., Grindlay and E. Schiebel. (2000). Nud1p links astral microtubule organisation and the control of exit from mitosis. EMBO J., 19: 6475-6488.

Pereira, G., T. Höfken, J. Grindlay, C. Manson and E. Schiebel. (2000). The Bub2p spindle checkpoint links nuclear migration with mitotic exit. Mol. Cell, 6: 1-10.

Schramm, C., S. Elliott, A. Shevchenko, A. Shevchenko and E. Schiebel. (2000). The Bbp1p/Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication. EMBO J., 19: 421-433.

Leroux, M.R., M. Fändrich, D. Klunker, K. Siegers, A.N. Lupas, J. Brown, E. Schiebel, C.M. Dobson and F.U. Hartl. (1999). MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin. EMBO J., 18: 6730-6743.

Pereira, G., U. Grueneberg, M. Knop and E. Schiebel. (1999). Interaction of the yeast g-tubulin complex binding protein Spc72p with Kar1p is essential for microtubule function during karyogamy. EMBO J., 18: 4180-4196.

Knop, M., K. Siegers, G. Pereira, W. Zachariae, B. Winsor, K. Nasmyth and E. Schiebel. (1999). Epitope tagging of yeast genes using a PCR-base strategy: more tags and improved practical routines. Yeast, 15: 963-972.

Elliott, S., M. Knop, G. Schlenstedt and E. Schiebel. (1999). Spc29p is a component of the Spc110p-subcomplex and is essential for spindle pole body duplication. Proc. Natl. Acad. Sci. USA., 96: 6205-6210.

Siegers, K., T. Waldmann, M. R. Leroux, K. Grein, A. Shevchenko, E. Schiebel and F.-U. Hartl. (1999). Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system. EMBO J., 18: 75-84.

Knop, M. and E. Schiebel. (1998). Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation. EMBO J., 17: 3952-3967.

Pereira, G., M. Knop and E. Schiebel. (1998). Spc98p directs the yeast gamma-tubulin complex into the nucleus and is subject to cell-cycle dependent phosphorylation on the nuclear side of the spindle pole body. Mol. Biol. Cell, 9:775-793.

Geissler, S., K. Siegers and E. Schiebel. (1998). Identification of a novel protein complex promoting formation of functional alpha- and gamma-tubulin. EMBO J., 17:952-966.

Knop, M. and E. Schiebel. (1997). Spc98p and Spc97p of the yeast gamma-tubulin complex mediate binding to the spindle pole body via their interaction with Spc110p. EMBO J., 16: 6985-6995.

Middendrop, S., A., Paoletti, E. Schiebel and M. Bornens. (1997). Identification of a new mammalian centrin gene, more closely related to Saccharomyces cerevisiae CDC31 gene. Proc. Natl. Acad. Sci. USA. 94: 9141-9146.

Knop, M., G. Pereira, S. Geissler, K. Grein and E. Schiebel. (1997). The spindle pole body component Spc97p interacts with the gamma-tubulin of Saccharomyces cerevisiae and functions in microtubule organization and spindle pole body duplication. EMBO J., 16: 1550-1564.

Geier, B.M, H. Wiech and E. Schiebel. (1996). Binding of centrins and yeast calmodulin to synthetic peptides corresponding to binding sites in the spindle pole body components Kar1p and Spc110p. J. Biol. Chem., 271: 28366-28374.

Wiech, H., B.M. Geier, T. Paschke, A. Spang, K. Grein, J. Steinkötter, M. Melkonian and E. Schiebel. (1996). Characterization of green algae, yeast and human centrins: Specific subdomain features determine functional diversity. J. Biol. Chem., 271: 22453-22461.

Spang, A., K. Grein and E. Schiebel. (1996). The spacer protein Spc110p targets calmodulin to the central plaque of the yeast spindle pole body. J. Cell Sci., 109: 2229-2237.

Geissler, S., G. Pereira, A. Spang, M. Knop, S. Souès, J. Kilmartin and E. Schiebel. (1996). The spindle pole body component Spc98p interacts with the g-tubulin-like Tub4p of Saccharomyces cerevisiae at the sites of microtubule attachment. EMBO J., 15: 3899-3911.

Spang, A., S. Geissler, K. Grein and E. Schiebel. (1996). The gamma-tubulin-like Tub4p of Saccharomyces cerevisiae is associated with the spindle pole body substructures that organize microtubules and is required for mitotic spindle formation. J. Cell Biol., 134: 429-441.

Spang, A., I. Courtney, K. Grein, M. Matzner and E. Schiebel. (1995). The Cdc31p-binding protein Kar1p is a component of the half bridge of the yeast spindle pole body. J. Cell Biol., 128: 863-877.

Spang, A., I. Courtney, U. Fackler, M. Matzner and E. Schiebel. (1993). The calcium-binding protein cell divison cycle 31 of Saccharomyces cerevisiae is a component of the half bridge of the spindle pole body. J. Cell Biol., 123: 405-416.

Schiebel, E. and W. Wickner. (1992). Preprotein translocation creates a halide anion permeability in the Escherichia coli plasma membrane. J. Biol. Chem., 267: 7505-7510.

Schiebel, E., A.J.M. Driessen, F.-U. Hartl and W. Wickner. (1991). ∆µH+ and ATP function at different steps of the catalytic cycle of preprotein translocase. Cell, 64: 927-939.

Hartl, F.-U., S. Lecker, E. Schiebel, J.P. Hendrick and W. Wickner. (1990). The binding cascade of SecB to SecA to SecY/E mediates preprotein targeting to the E. coli plasma membrane. Cell, 63: 269-279.

Brundage, L., J.P. Hendrick, E. Schiebel, A.J.M Driessen and W. Wickner. (1990). The purified E. coli integral membrane protein SecY/E is sufficient for reconstitution of SecA-dependent precursor protein translocation. Cell, 62: 649-657.

Schiebel, E., H. Schwarz and V. Braun. (1989). Subcellular location and unique secretion of the hemolysin of Serratia marcescens. J. Biol. Chem., 264: 16311-16320.

Schiebel, E. and V. Braun. (1989). Integration of the Serratia marcescens haemolysin into human erythrocyte membranes. Mol. Microbiol., 3: 445-453.

Poole, K., E. Schiebel and V. Braun. (1988). Molecular characterization of the hemolysin determinant of Serratia marcescens. J. Bacteriol., 170: 3177-3188.

Braun, V., B. Neuss, Y. Ruan, E. Schiebel, H. Schoeffler and G. Jander. (1987). Identification of the Serratia marcescens hemolysin determinant by cloning into Escherichia coli. J. Bacteriol., 169: 2113-2120.

Review articles and comments


Partscht, P. and E. Schiebel. (2023). The diverging role of CDC14B: from mitotic exit in yeast to cell fate control in humans. EMBO J (2023)e11436

Dang, H. and E. Schiebel. (2022). Emerging roles of centrosome cohesion. Open Biol 2022 Oct.;12(10). doi: 10.1098/rsob.220229.

Boehler, A., B.J.A. Vermeulen, M. Würtz, E. Zupa, S. Pfeffer, and E. Schiebel. (2021). The gamma-tubulin ring complex: Deciphering the molecular organization and assembly mechanism of a major vertebrate microtubule nucleator. BioEssays

Liu, P., M. Würtz, E. Zupa, S. Pfeffer, and E. Schiebel. (2021). Microtubule nucleation: The waltz between gamma-tubulin ring complex and associated proteins. Curr Opin Cell Biol. 68:124-131.

Zupa, E., P. Liu, M. Würtz, E. Schiebel and S. Pfeffer. (2020). The structure of the gamma-TuRC: a 25-years-old molecular puzzle. Curr Opin Struct Biol. Sep 28;66:15-21.

Pfeffer, S. and E. Schiebel. (2020). Einblicke in die Entstehung von Mikrotubuli. BIOspektrum: 02.20, 26. Jahrgang, S. 145-147.

Remo+, A., X. Li+, E. Schiebel* and M. Pancione*. (2020). The centrosome linker and its role in cancer and genetic disorders. Trends in Mol Med., Febr.18,2020. doi: * Co-corresponding authors. + joint first authors.

Rüthnick, D. and E. Schiebel. (2018). Duplication and nuclear envelope insertion of the yeast microtubule organizing centre, the spindle pole body. Cells, May 10;7(5). pii: E42. doi: 10.3390/cells7050042.

Cerikan, B. and E. Schiebel. (2016). DOCK6 inactivation highlights ISGylation as RHO-GTPase balancer. Cell Cycle, Nov. 10:1-2.

Pereira, G. and E. Schiebel. (2016). Mitotic exit: Determining the PP2A dephosphorylation program. J. Cell Biol., 214(5), 08-29-2016.

Rüthnick, D. and E. Schiebel. (2016). Duplication of the yeast spindle pole body once per cell cycle. Mol. Cell. Biol., 36:1324-1331.

Lin, T., A. Neuner and E. Schiebel. (2015). Targeting of gamma-tubulin complexes to microtubule organizing centers: conservation and divergence. Trends Cell Biol., 25:249-316.

Schiebel, E. (2014). DNA im Zellkern: Chromatin und Chromosomen. Kap. 7, S. 139-157. In "Molekulare Genetik", 10. Auflage, Thieme Verlag, Stuttgart.

Schiebel, E. (2014). Segregation der Chromosomen: Zellzyklus, Mitose und Meiose. Kap. 9, S. 197-215. In "Molekulare Genetik", 10. Auflage, Thieme Verlag, Stuttgart.

Agircan, F.G., E. Schiebel and B.R. Mardin. (2014). Separate to operate: control of centrosome positioning and separation. Philos. Trans. R. Soc. Lond. B. Biol. Sci., 369:1650. pii: 20130461.

Seybold, C. and E. Schiebel. (2013). Spindle pole bodies. Curr. Biol., 23:R858-860.

Mardin, B.R. and E. Schiebel. (2012). Breaking the ties that bind: New advances in centrosome biology. J. Cell Biol., 197:11-18.

Mocciaro, A. and E. Schiebel. (2010). Cdc14: a highly conserved family of phosphatases with non-conserved functions? J. Cell Sci., 123:2867-2876.

Roostalu, J., E. Schiebel and A. Khmelinskii. (2010). Cell cycle control of spindle elongation. Cell Cycle, 9:1084-1090.

Khmelinskii, A. and E. Schiebel. (2009). Chromosome segregation: monopolin goes spindle. Curr. Biol., 19:R482-R484.

Khmelinskii, A. and E. Schiebel. (2008). Assembling the spindle midzone in the right place at the right time. Cell Cycle, 7:283-286.

Maekawa, H. and E. Schiebel. (2004). CLIP-170 family members: a motor-driven ride to microtubule plus ends. Dev. Cell, 6:746-748.

Pereira, G. and E. Schiebel. (2004). Cdc14 phosphatase resolves the rDNA segregation delay. Nature Cell Biol., 6:473-475.

Usui, T. and E. Schiebel. (2001). Regulating microtubule properties by modifying their organising minus-ends. Mol. Cell. 8: 931-932.

Pereira, G. and E. Schiebel. (2001). The role of the yeast spindle pole and the mammalian centrosome in regulating late mitotic events. Curr. Opin. Cell Biol., 13: 762-769.

Schiebel, E. (2000). Two new tubulins differ in a split decision. Nature Cell Biol., 1: E3-E4.

Schiebel, E. (2000). gamma-Tubulin complexes: binding to the centrosome, regulation and microtubule nucleation. Curr. Opin. Cell Biol., 12: 113-118.

Siegers, K. and E. Schiebel. (2000). Purification of GimC from Saccharomyces cerevisiae. In Chaperonin Protocols, “Methods in Molecular Biology”, Vol. 140, 185-193, Human Press, Inc., Totowa NJ, USA.

Knop, M., G. Pereira and E. Schiebel. (1999). Microtubule organization by the budding yeast spindle pole body. Biol. Cell, 91: 291-304.

Winsor, B. and E. Schiebel. (1997). An overview of the Saccharomyces cerevisiae microfilament and microtubule cytoskeleton. Yeast, 13: 399-434.

Pereira, G. and E. Schiebel. (1997). Centrosome microtubule nucleation. J. Cell Sci., 110: 295-300.

Schiebel, E. and M. Bornens. (1995). In search of a function for centrins. Trends Cell Biol., 5: 197-201.

Driessen, A.J.M., L. Brundage, J.P. Hendrick, E. Schiebel, and W. Wickner. (1991). Preprotein translocase of Escherichia coli: Solubilization, purification and reconstitution of the integral membrane subunits SecY/E. Meth. Cell Biol., 34: 147-165.

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